Hormone Replacement Therapy
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| A book report on What Your Doctor May Not Tell You About Menopause
"menopause (climacteric) n. the time in a
woman's life when the ovaries cease to produce an egg cell every four weeks and therefore
menstruation ceases and the woman is no longer able to bear children. The menopause can
occur at any age between the middle thirties and the late fifties. Menstruation may
decrease gradually in successive periods or the intervals between periods may lengthen;
alternatively there may be a sudden and complete stoppage of the monthly periods. At the
time of the menopause there is a change in the balance of sex hormones in the body, which
sometimes leads to hot flushes, palpitations, and dryness of the mucous membrane lining
the vagina. Some women may also experience emotional disturbances. These symptoms may be
relieved by administering the appropriate estrogenic hormones (hormone replacement
therapy). -menopausal adj."
Let us first address hormone
replacement therapy hereafter referred to as HRT.
When most doctors mention the word "estrogen" they use it
synonymously with the prescription drug called Premarin ®It should be understood that Premarin® appears to the human body as an alien substance, which, of course, it is.The
following is an excerpt from the book Natural Hormone Replacement by Jonathan V.
Wright, M.D. & John Morgenthaler, which is offered for sale and every
woman should read:
"A Disturbing Undercurrent
Despite the overwhelming clinical and marketing success of Premarin® and other forms of synthetic "estrogen," there
has been, almost from the start, a disturbing undercurrent of doubt about the safety of
conventional "estrogen" replacement therapy. That doubt can be summed up in one
The first cancer associated with "estrogen" replacement
therapy was cancer of the endometrium (the lining the uterus). If we look up Premarin®'s legally required labeling2, the first thing striking the eye is a large boxed-in area strategically placed
to make sure it's the first thing we see when we read this document. The actual wording of
the Premarin® cancer warning is shown below. A variation of this warning appears on the
labels of all "estrogens" not occurring naturally in humans, as well as the
popular estrogen "patch".
Official Premarin® Warning Label
Premarin® is a registered trademark of Wyeth-Ayerst Laboratories
Estrogens Have Been Reported To
Increase the Risk of Endometrial Carcinoma
Three independent, case-controlled studies have reported an increased
risk of endometrial cancer in Post-menopausal women exposed to exogenous estrogens for
more than one year. This risk was independent of the other known risk factors for
endometrial cancer. These studies are further supported by the finding that incidence
rates of endometrial cancer have increased sharply since 1969 in eight different areas of
the United States with population-based cancer-reporting systems, an increase which may be
related to the rapidly expanding use of estrogens during the last decade.
The three case-controlled studies reported that the risk of endometrial
cancer in estrogen users was about 4.5 to 13.9 times greater that in nonusers. The risk
appears to depend on both duration of treatments and on estrogen dose. In view of these
findings, when estrogens are used for the treatment of menopausal symptoms, the lowest
dose that will control symptoms should be utilized and medication should be discontinued
as soon as possible. When prolonged treatment is medically indicated, the patient should
be reassessed, on at least a semi-annual basis, to determine the need for continued
therapy. Although the evidence must be considered preliminary, one study suggests that
cyclic administration of low doses of estrogen may carry less risk that continuous
administration. It therefore appears prudent to utilize such a regimen.
Close clinical surveillance of all women taking estrogens is important.
In all cases of undiagnosed persistent or recurring abnormal vaginal bleeding, adequate
diagnostic measures should be undertaken to rule out malignancy.
There is no evidence at present that "natural" estrogens are
more or less hazardous than "synthetic" estrogens at equal-estrogenic doses.
There are Two Key Points in This Warning:
First, taking Premarin® for more than a year increases the risk of
cancer of the endometrium by as much as 14%. Well-controlled studies have shown that the
risk of endometrial cancer is cumulative, rising at a rate of four to five cases per 1,000
Premarin® users with each year of use. By the
fifth year of Premarin® use, a woman might be
facing a 2% risk, and by her tenth year, her risk might be as high as 4% or 5%. Second,
other forms of "synthetic" estrogen carry about the same risk.
After many years of prescribing "unopposed estrogen"
("estrogen" with no other accompanying hormones), and probably causing tens of
thousands of women to develop cancer as a result, physicians finally discovered that the
risk of developing endometrial cancer due to estrogen replacement can be reduced by also
replacing missing progesterone. Progesterone can block or "oppose" estrogen's
cancer causing tendencies.
Nature and Creation have known this all along! (Sometimes, we in medical
practice are a bit slow). As long as there have been human bodies, and very likely longer,
estrogen and progesterone have participated in the intricate dance of the menstrual cycle.
The rise and fall of each is intimately linked to the rise and fall of the other. They're
like two sides of a coin. To replace one without the other is an invitation to trouble
which was too long ignored by nearly all medical doctors.
The "progestogen" (NOT progesterone, but more about that later
also) physicians most often prescribe now is also a synthetic one called
medroxyprogesterone, which goes by the brand name Provera®. The combination of synthetic "estrogen" and
Provera® called "hormone" replacement therapy, or HRT, is standard practice
among most doctors today.
While the addition of Provera® may minimize the risk of endometrial cancer due to patentable
"estrogen," it does nothing to lessen another serious risk of estrogen"
replacement: breast cancer. Women on a regimen of standard HRT using synthetic
"hormones" like Premarin (Reg.) and
Provera® may increase their risk of breast cancer by as much as 30%, according to some
estimates. In. real numbers, this means that for every 1,000 women using one of these
drugs, 30 will eventually develop breast cancer from the HRT itself.
Not good odds, but many doctors observe that without
"estrogen," the risks of heart disease and osteoporosis, and their
complications, are far greater."
The authors go on to discuss the use of progestins on the last page of
their book, Natural Hormone Replacement as follows:
"Provera and Heart Disease:
Worse Than No Treatment at All
Heart disease is responsible for at least three-fourths of the deaths in
postmenopausal women. Although much evidence suggests that estrogen replacement helps
reduce the risks associated with heart disease, new data confirms that the common practice
of taking the synthetic progestin Provera® along with "estrogen" to minimize
the risk of endometrial cancer may be increasing women's risk of suffering a heart attack
to an unacceptable level. Natural progesterone, however provides cancer protection but
carries no such risk.
This conclusion comes from a new study carried out in rhesus monkeys at
the Oregon Regional Primate Research Center. Eighteen monkeys had their ovaries removed to
simulate menopause. They were then put on a hormone replacement regimen that included
estradiol plus either Provera® or natural progesterone. After 4 weeks, the researchers
injected a substance that causes coronary arteries (which supply the heart with blood) to
constrict, cutting off the flow of blood to the heart muscle.
The researchers reported that the animals receiving Provera® would have
died within minutes had they not received a protective drug treatment. The same thing
happened in those animals that received no hormone replacement. By contrast, those monkeys
that received natural progesterone quickly recovered from their simulated heart attack
with no protective drug treatment.
"The big surprise," noted the primary author of the paper in
an interview in Science News, is that Provera® poses such a "huge risk."
"This is a really dangerous drug."
The results of a British study in women show that this conclusion is not
limited to monkeys. Sixteen postmenopausal women with coronary artery disease also
received "hormone" replacement that included an "estrogen" plus either
Provera® or natural progesterone. Those who received natural progesterone were able to
exercise significantly longer on a treadmill test before developing symptoms indicating
reduced blood flow to their hearts. Noted one researcher, in terms of heart disease
protection, Provera is 'worse than no treatment at all.' "
Again, every women should read this book!
To go directly to our book store click here
You can find a drug's labeling on a small sheet
of paper that comes packaged with every drug. If your pharmacist does not automatically
give you a package insert, or Pi, when you fill a prescription you should ask him/her for
it. The PI, which usually comes folded like a miniature road map and is printed in
annoyingly tiny type, contains lots of interesting information about a drug. For example,
it includes everything the drug company would like doctors to know about their drug that
the FDA will allow them to say. It may also contain a few things they would rather not say
that the FDA insists that they do. You can find PIs for most drugs in a book called the
Physicians' Desk Reference, or PDR, which you can purchase or find in any library.
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Book review on Natural Hormone Replacement
Midwest Book Review :
Natural Hormone Replacement For Women Over 45 shows how natural hormone replacement offers
a safe and effective alternative for the treatment of menopause. Conventional hormone
replacement treatment as prescribed by most medical doctors in the United States, relies
on unnatural versions of the hormones progesterone and estrogen that are dangerous and
completely foreign to a woman's body. Risky and unpleasant, conventional hormone
replacement treatment has long been women's only choice because of the influence of the
drug companies. Natural Hormone Replacement For Women Over 45 provides compelling evidence
that natural hormone replacement provides all the benefits of conventional treatment, but
with drastically reduced risks of unwanted side effects and cancer. Readers of Natural
Hormone Replacement For Women Over 45 will learn how to end hot flashes and other
discomforts of menopause; cut the risk of osteoporosis, heart disease, and cancer; extend
their youthful years; invigorate their sex life; decrease the risk of Alzheimer's disease
and senility; locate a pharmacy that prepares natural hormones; and find a physician who
prescribes them. Natural Hormone Replacement For Women Over 45 is must reading for all
women facing menopause and the infirmities of the aging process.
Welcome to the Age of Natural Hormone Replacement
Hormones of the Menstrual Cycle
Hormones: Patentable, Natural, or Natural for Horses?
Relieving Common Menopausal Symptoms
Preventing & Reversing Osteoporosis
Preventing Heart Disease
Testosterone & Other Androgens: Not Just for Men
Hormone Replacement & Cancer
Estrogen & Senility
Using Natural Hormones
Natural Hormones from Foods & Herbs
- Table of Contents
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Book Report on: What Your Doctor May Not Tell You
email@example.com , 04/29/97, rating=10:
The most important book on women's health I've ever read.
The author, a medical doctor with 30 years of private practice experience, decided that he
wasn't being very effective in helping his women patients deal with unpleasant
premenopausal and menopausal symptoms. He began to research the research on hormone
balance, HRT (hormone replacement therapy), and the way the medical and pharmaceutical
industries deal with the "disease" of menopause and "female problems."
What he discovered was that treating menopause as an "estrogen deficiency
disease" was exactly wrong. In fact he argues that premenopausal and menopausal women
are much more likely to be in a state of "estrogen excess" relative to levels of
progesterone, which are often close to zero. Estrogen excess leads to weight gain, mood
disorders, endometriosis, low sex drive, fybrocystic breasts, heart disease, and
osteoporosis. Yet what the most doctors and drug companies offer to do is to increase
estrogen levels with synthetic hormones made with pregnant mare's urine and synthetic
progestins. While this may temporarily relieve certain symptoms like vaginal dryness and
hot flashes, this HRT regime ultimately leads to worse side effects, including increased
breast cancer risk, increased bone loss, increased overall cancer risk, and increased
heart disease risk. Yet we are told that HRT is the only way to prevent osteoporosis and
heart disease! John Lee explodes these myths and many more, including that any woman needs
anhysterectomy unless she has cancer (yet over 600,000 are done in the US each year,
meaning 600,000 potential new consumers of HRT!!)Over the years he has helped thousands of
women restore their hormone balance and their lives with diet, exercise, and the use of
natural progesterone (usually applied topically in a cream). He convincingly demonstrates
that this regimen can increase bone density (even in women in their 70's and 80's!),
reduce fibrocystic breast problems and the risk of breast and other cancers, reduce the
risk of heart disease, increase feelings of well-being, sex drive and energy levels,
reduce PMS, migraine headaches and unpleasant menopausal symptoms. He also systematically
reveals the role of "xenoestrogens," the thousands of synthetic chemicals in the
environment and our food supply which mimic our bodies' hormones and which increasingly
create havoc with our systems.But don't just take my word for it. Please go out and read
this book, then pass it along to other women you care about, including your teenage
daughters and your mothers.
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